Brainstem Encephalitis With Low-Titer Acetylcholine Receptor Antibodies Mimicking Myasthenia Gravis

IgG1 antibodies to acetylcholine receptors in ‘seronegative’ myasthenia gravis†

Only around 80% of patients with generalized myasthenia gravis (MG) have serum antibodies to acetylcholine receptor [AChR; acetylcholine receptor antibody positive myasthenia gravis (AChR-MG)] by the radioimmunoprecipitation assay used worldwide. Antibodies to muscle specific kinase [MuSK; MuSK antibody positive myasthenia gravis (MuSK-MG)] make up a variable proportion of the remaining 20%. Th...

Pseudoabducens palsy mimicking myasthenia gravis.

To cite: Liao B, Rodriguez RM, Metrus NR, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015209392 DESCRIPTION A 62-year-old right-handed Caucasian man with hypertension, diabetes and alcoholic fatty liver presented with sudden onset double vision. Physical examination on admission was inward and downward deviation of the left eye, obvious on forward gaze...

Myasthenia gravis: acetylcholine-receptor antibody titres after thymectomy.

Fetal acetylcholine receptor inactivation syndrome and maternal myasthenia gravis.

Fetal acetylcholine receptor inactivation syndrome is a rare condition occurring in newborns of myasthenic mothers, characterized by bulbar and facial weakness after recovery from the generalized muscle weakness. Antibodies against fetal subunit of acetylcholine receptor seem to have a pathogenetic role leading to long-lasting injury in vulnerable muscle groups. We report a girl, born to a myas...

HLA antigens and acetylcholine receptor antibodies in penicillamine induced myasthenia gravis.

Antibodies to the acetylcholine receptor and HLA antigens have been studied in patients with myasthenia gravis occurring in association with penicillamine treatment. The properties of the antiacetylcholine receptor in these patients differed from those in patients with idiopathic myasthenia gravis in terms of specificity and affinity. These patients had an increased prevalence of HLA Bw35 and D...